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Albiglutide

Albiglutide is a GLP-1 receptor agonist formerly marketed in the US as TANZEUM for type 2 diabetes. Its clinical evidence remains relevant despite commercial discontinuation.

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At a glance

Evidence stage
Approved use
Regulatory status
TANZEUM received US approval for adult type 2 diabetes, but FDA and manufacturer records list it as discontinued; it is not a currently marketed alternative.
Research context
Albiglutide is a GLP-1 receptor agonist formerly marketed in the US as TANZEUM for type 2 diabetes. Its clinical evidence remains relevant despite commercial discontinuation.

What this is

  • Albiglutide is a GLP-1 receptor agonist formerly marketed in the US as TANZEUM for type 2 diabetes. Its clinical evidence remains relevant despite commercial discontinuation.

What this isn't

  • A recommendation to use, prepare, combine, or administer a product
  • Evidence that a related molecule or a differently formulated product has the same effects

Key terms

Albiglutide is a GLP-1 receptor agonist formerly marketed in the US as TANZEUM for type 2 diabetes. Its clinical evidence remains relevant despite commercial discontinuation.

Albiglutide activates GLP-1 receptors, enhancing glucose-dependent insulin secretion, reducing glucagon secretion, and affecting gastric emptying. Its albumin-linked structure prolongs exposure compared with native GLP-1. These actions explain a diabetes treatment rationale, but neither prolonged exposure nor a shared receptor makes it interchangeable with every other GLP-1 medicine. Product label.

Evidence limits

How to read the evidence

GSK states that TANZEUM ceased sale in July 2018, and FDA lists the product discontinued. Manufacturer record. Discontinuation and evidence of cardiovascular benefit can both be true. Historical research should not imply access to a current licensed product or justify sourcing an unregulated substitute. Product-specific scope.

Sources appraised 2026-10-28. Educational information; not medical advice. Study findings apply to the populations, preparations and outcomes described.

External sources and citations

  1. TANZEUM prescribing information (FDA, 2017)
  2. HARMONY Outcomes randomized albiglutide trial
  3. FDA licensed and discontinued biologic product list, June 2026
  4. GSK Tanzeum discontinuation record
  5. FDA application BLA125431 — discontinued TANZEUM

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