Dipeptide diaminobutyroyl benzylamide diacetate
Dipeptide diaminobutyroyl benzylamide diacetate, sold as SYN-AKE, is a synthetic cosmetic peptide mimic. Its name does not mean a product contains snake venom.
At a glance
- Regulatory status
- Cosmetic ingredient; cosmetic marketing or an ingredient listing is not FDA drug approval. Claims and intended use determine regulatory treatment.
- Research context
- Dipeptide diaminobutyroyl benzylamide diacetate, sold as SYN-AKE, is a synthetic cosmetic peptide mimic. Its name does not mean a product contains snake venom.
What this is
- Dipeptide diaminobutyroyl benzylamide diacetate, sold as SYN-AKE, is a synthetic cosmetic peptide mimic. Its name does not mean a product contains snake venom.
What this isn't
- A recommendation to use, prepare, combine, or administer a product
- Evidence that a related molecule or a differently formulated product has the same effects
Dipeptide diaminobutyroyl benzylamide diacetate, sold as SYN-AKE, is a synthetic cosmetic peptide mimic. Its name does not mean a product contains snake venom.
The ingredient is marketed around a venom-inspired neuromuscular hypothesis. However, an effect of a natural venom peptide cannot be assumed for a synthetic mimic in a topical serum. Establishing that claim would require evidence for this exact molecule, its skin penetration and its biological target at the exposure achieved.
Evidence limits
How to read the evidence
Interpret the proposed mechanism separately from the measured endpoints. Improved wrinkle scores for a multi-active serum can be useful product-level evidence while leaving the contribution of an individual ingredient unresolved. The evidence reviewed here does not establish which ingredient produced the change or whether another SYN-AKE product would reproduce it.
Sources appraised 2026-10-28. Educational information; not medical advice. Study findings apply to the populations, preparations and outcomes described.
External sources and citations
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