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Fragment 176-191

Fragment 176–191 refers to the native C-terminal segment of human growth hormone. It must be distinguished from full-length growth hormone and the modified analogue AOD-9604.

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At a glance

Regulatory status
Research reference with unresolved source identity; the reviewed sources do not establish a human therapeutic indication or an approved weight-loss product.
Research context
Fragment 176–191 refers to the native C-terminal segment of human growth hormone. It must be distinguished from full-length growth hormone and the modified analogue AOD-9604.

What this is

  • Fragment 176–191 refers to the native C-terminal segment of human growth hormone. It must be distinguished from full-length growth hormone and the modified analogue AOD-9604.

What this isn't

  • A recommendation to use, prepare, combine, or administer a product
  • Evidence that a related molecule or a differently formulated product has the same effects

Fragment 176–191 refers to the native C-terminal segment of human growth hormone. It must be distinguished from full-length growth hormone and the modified analogue AOD-9604.

The name identifies a portion of the growth hormone sequence, not a demonstrated clinical mechanism. AOD-9604 instead combines residues 177–191 with an N-terminal tyrosine, as described in FDA's chemical review. That modification matters when assigning studies. Similar names and a shared sequence segment do not make the molecules pharmacologically or clinically interchangeable.

Evidence limits

How to read the evidence

Assigning evidence requires confirmation of the actual sequence and experimental material, not just a paper's title or product name. The reviewed sources leave native-fragment efficacy unresolved. Full-length growth hormone and AOD-9604 studies cannot fill that gap by analogy or establish selective fat-metabolism benefits without growth-hormone risks. No evidence stage is assigned here because the cited laboratory paper does not securely identify the native fragment.

Sources appraised 2026-10-28. Educational information; not medical advice. Study findings apply to the populations, preparations and outcomes described.

External sources and citations

  1. Paper labeled GH fragment 176–191: reported sequence identity mismatch. 2022
  2. FDA AOD-9604 review: chemical identity and limitations. 2024

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